KMID : 0385019970130020187
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Korean Journal of Laboratory Animal Science 1997 Volume.13 No. 2 p.187 ~ p.190
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Effects of Alkaline lonized Water on Spontaneously diabetic GK-rats fed Sucrose
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Yokoyama Kazuhito
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Abstract
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This study was carried out to evaluate the effects of alkaline ionized water (AIW) on spontaneouely diabetic GH-rate fed sucrose for aggravation of diabetes mellitus. One half. of the 32 GH-rats was given AIW and the other was given tap water (TW) ad lib. These two groups were farther divided into two subgroups by fed with or without 30% sucrose solution (8 in each group). In blood glucose level, sucrose fed TW group was significantly higher than the other groups. Sucrose fed both AIW and TW groups were significantly increased in body weight as compared to TW group. In serum malondialdehyde (MDA), a marker of lipid peroxide, sucrose fed TW group was significantly hiker than AIW and TW groups. It is suggested that AIW supplementation may inhibit the increase of blood glucose and lipid peroxide levels in diabetes mellitus.
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